#precision_longevity
Shrinking Thigh and Calf Size Was Linked to Faster Muscle and Mobility Decline in a Small NIH Study
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A small NIH body-scan study of 302 volunteers found that smaller thigh and calf size went with older age and, in a side analysis, with slower walking and weaker knee strength over time. The study was exploratory and did not test home tape measures. Read more…
Brain Aging: What Habits and Sleep Research Show
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Bilingualism, meditation, and sleep problems have each been studied in relation to brain aging or dementia risk, and subjective age in relation to general health. Most findings are associations rather than proof. Read more…
Once-Weekly HIIT and Fat Loss: What a 315-Adult Trial Found
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A randomized trial of 315 adults found that HIIT once a week lowered fat mass by about 0.8 kg after 16 weeks versus a no-exercise control, but the fat-mass gap was gone four months after the program ended. Read more…
Heart Disease, Frailty, and Memory Loss Often Overlap
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A major ACC statement says heart disease, frailty, and cognitive decline in older adults often share underlying aging processes, and recommends assessing them together while noting the evidence is limited. Read more…
Lemon Water and Weight Loss: What the Research Shows
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Lemon water has not been shown to burn fat, but swapping it for sugary drinks may help, and here is what the studies say. Read more…
BPC-157 and TB-500: What FDA Reviewers Found
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FDA staff reviewed seven popular peptides in July 2026 and found little human evidence on whether BPC-157 or TB-500 work or are safe. An advisory committee voted 8-6 in favor of adding BPC-157, as reported by ABC News; the vote is advice only. Read more…
